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Clinical trials: Conducted in three rigorous phases, often managed by Contract Research Organisations (CROs) Phase 1: Tests the drug in a small group (20100) of healthy volunteers to check basic safety and dosages Phase 2: Administered to a larger group (100300) of patients to test efficacy and potential side effects

The abdomen typically provides the most consistent absorption, with areas at least two inches from the navel being optimal

10.1002/14651858.CD000528 Cochrane Data Syst