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It could point to several things: A different cause: your fatigue might stem from thyroid problems, iron deficiency, or sleep apnea rather than B12

The British Society of Gastroenterology (BSG) 2025 guidelines now recommend screening for B12 and folate in high-risk IBD patients , especially if: Youve had ileal surgery or inflammation Youre on certain medications Youve had unexplained fatigue You have signs of neuropathy or anemia In Dubai, we see many patients who havent had these checked until they come in with persistent fatigueeven after their iron has improved

The FDA panel has deferred the approval of the drug, pending the conduction of a long-term study demonstrating cardiovascular safety [243] (Table 3 )

Its effectiveness also extends to improved insulin secretion and reduced glucagon levels

Baxter, Brandon (June 3, 2014)