Bioorg Chem
& Takahashi, H
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HTyr butyrate acts by inhibiting the ubiquitin E3 ligase that targets Nrf2 for proteasomal degradation, after reacting with the cysteine thiols of Kelch-like ECH-associated protein 1 (Keap1) that is part of the ubiquitin complex [143,175]
within 10 generations)