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20 21 Getting the Right Support : As these medications become more popular for the treatment of obesity and diabetes, the integration of professional nutrition and health coaching guidance has emerged as a critical factor in optimizing outcomes and achieving sustained results

These medications work by mimicking the action of endogenous GLP-1, an incretin hormone released from the intestinal L-cells in response to food intake

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Initial Combination Therapy with Metformin A total of 1091 patients with type 2 diabetes and inadequate glycemic control on diet and exercise participated in a 24-week, randomized, double-blind, placebo-controlled factorial study designed to assess the efficacy of sitagliptin as initial therapy in combination with metformin

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