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Production of plasma d9-TMA and d9-TMAO from the d9-BB was markedly higher in the mice that had been on the BB supplemented diet, consistent with functional induction of microbes optimized to use BB as fuel source following long-term dietary exposure (Figure 6B)

J9310 Vitamin B12 (cyanocobalamin): B12-deficiency neuropathy

Retatrutide discontinuation rates at the highest dose are modestly higher but broadly comparable to the GLP-1 agonist class

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It mimics GLP-1, a hormone involved in appetite regulation and eating behavior