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Sonication refers to the process of applying sound energy to agitate particles or discontinuous fibers in a liquid

However people with low homocysteine, mostly don't have these negative reactions to taking B12 as an injection or oral

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Aschner M., Martins A.C., Oliveira-Paula G.H., Skalny A.V., Zaitseva I.P., Bowman A.B., Kirichuk A.A., Santamaria A., Tizabi Y., Tinkov A.A

It is always recommended that patients consult with their healthcare provider before initiating any new supplement regimen

Thus, scientists must note that unanticipated reactions may emerge as research progresses