In these situations, oral B12 supplements are often useless because the digestive system can't properly absorb the nutrient
10.1021/acs.jcim.0c01227 24 BooneK
As an alternative, however, and as confirmed by our results, increasing the permeability of the cytoplasmic membrane by electroporation induces a selective and efficient release of compounds located in the cytoplasm of microbial cells such as yeast or microalgae without disintegrating the cell wall ( Several studies have demonstrated the benefit of the application of a PEF treatment for the subsequent extraction of different compounds from yeast, such as proteins, carotenoids, glutathione, and recombinant proteins with antitumoral effect ( Release of mannoproteins into the medium in which the yeast biomass was re-suspended required enzymatic hydrolysis of the cell wall
Their main function is to facilitate the transport of fatty acids to the mitochondria of cells, where they are converted into energy
By 2024, over 765 million people worldwide are projected to suffer from osteoarthritis, with traditional cartilage repair techniques failing in up to 87.5% of complex cases
