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For comparison: Consistent diet and exercise: 5-10% body weight over 6 months (evidence-based lifestyle programs) Pharmaceutical GLP-1 agonists: 10-20% body weight over 12-18 months Berberine/fiber supplements: 1-3 pounds over 3 months Individual variation existssome people respond better than others

It is worth reporting the rest of that trial honestly too: its primary insulin-sensitivity endpoint was not met across the group as a whole

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