Certain beneficial gut microbes, such as Lactobacillus and Bifidobacterium , have been shown to stimulate the vagus nerve, leading to anxiolytic and antidepressant-like effects through the modulation of neurotransmitter release and HPA axis regulation [124, 150]
If your body cannot absorb the nutrients you take, the timing matters very little
Hydration Focused Fluids Fluids delivered directly to the bloodstream, bypassing the gut and guaranteeing instant replenishment
That said, its always a good idea to check with your healthcare provider before shifting your schedule, since individual factors like your dosage and any other medications you take can affect whats appropriate for you
The dose at which supplementation shifts appetite-regulating pathways, if it occurs, is unclear