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In certain embodiments, the enhanced viscosity formulation is characterized by a phase transition between room temperature and body temperature (including an individual with a serious fever, e.g., up to about 42 C.)

The combined effects can produce excessive sedation or unpredictable interactions

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Pisetpackdeekul P, et al

IGF-LR3 (Insulin-like Growth Factor 1, Long Arg3) is a synthetic IGF-1 analogue carrying a 13-residue N-terminal extension and an arginine swap at position 3. Together these changes sharply lower affinity for IGF-binding proteins, lengthening functional half-life and improving receptor availability making it a workhorse in proliferation and anabolic-signalling research