doi: 10.1007/5584_2016_53
154 Orexins are also involved in brain pathways related to appetite, reward, fear, and cognition.155 Orexin deficiency causes a type of narcolepsy
It can be more about feels and looks than repeatable measurement
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1991 (landmark Italian trial): A double-blind, placebo-controlled trial involving 130 patients with Alzheimer's disease demonstrated that one year of ALCAR treatment resulted in a slower rate of deterioration compared to placebo across 13 of 14 outcome measures, including significant improvements in the Blessed Dementia Scale, logical intelligence, verbal critical abilities, long-term verbal memory, and selective attention [5][17]
