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Additional reported effects include antioxidant activity, genomic regulatory effects, and immune modulation [1]
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Novel delivery systems may improve stability, but consistent systemic exposure remains a primary challenge
Semaglutide medications work by activating the GLP-1 receptor alone, while tirzepatide medications activate both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor, creating what is commonly described as a dual incretin mechanism
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