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FEBS Lett (2004) 572:28993

Treatment with tirzepatide slowed the decline in the estimated glomerular filtration rate (eGFR) and reduced the urine albumin-creatinine ratio (UACR) in a clinically meaningful way compared with insulin glargine

This is called glossitis

GHK (glycyl-L-histidyl-L-lysine) is a naturally occurring peptide found in human serum with levels averaging 200 ng/ml at age 20 but declining to an average of 80 ng/ml by age 60