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Newer T2DM management regimens that include both incretin-based treatments and SGLT2 inhibitors are becoming well-established options due to their novel and complementary mechanisms of action, robust reductions in HbA1c levels, efficacy in reducing body weight and BP, and generally good safety profile

Potential Benefits & Side Effects Observations from limited and dated preclinical and clinical literature

Huang C, Verhulst S, Shen Y, Bu Y, Cao Y, He Y, et al

"If we can kind of, like, tease out what is the effect of weight loss versus what is the direct effect of these medications on the upper airway, that will be very interesting." The most common side effects of GLP-1 drugs, including tirzepatide, are nausea, vomiting, diarrhea and constipation

Tailoring supplementation to individual nutritional gaps and health conditions, under medical guidance, can enhance daily functioning