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Because HbF helps keep red blood cells from sickling, those who naturally make larger amounts of foetal haemoglobin (HbF) typically experience less severe symptoms (Donaldson et al., 2001)

157 ACADSB negatively regulates the expression of GPX4 and glutathione reductase in colon cancer cells, and overexpression of ACADSB increases the concentration of MDA, Fe 2+ and lipid peroxides, inducing cell ferroptosis, and inhibiting the migration and invasion of CRC cells