Bauer M, Herbarth O, Aust G, Hengstler JG, Dotzauer A, Graebsch C, et al
Transition metalbased carriers (e.g., MnO, Cu 2 , Fe 3 ) provide an additional layer of functionality, as they can both deplete intracellular GSH and generate reactive oxygen species, thereby amplifying oxidative stress within tumors
Cell Stress Chaperones 25 (2), 277285
We have taken traditional glutathione and enhanced the molecule to become fat-soluble, this means skin cells are able to absorb it more easily and it can work more effectively
Bioavailability also is modulated by oxidation status, as a stabilized version of the reduced form of MB displays markedly increased brain uptake, which has been factored into a recent clinical trial to be discussed in a subsequent section [14,15]