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The cardiovascular risk among individuals with severely elevated lipoprotein(a) is comparable to that associated with familial hypercholesterolemia, emphasizing the importance of early identification of these individuals, noted Ask Tybjrg Nordestgaard, PhD, from Brigham and Womens Hospital in Boston, and co-workers

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Genetic variation in GLP-1 receptor signaling, GIP pathway sensitivity, and metabolic efficiency influences both therapeutic response and adverse reaction intensity

These include pancreatitis, gallbladder problems, bowel obstruction, vision problems, kidney injury, and severe allergic reactions