Int J Mol Sci 23:4259
Glycine can also be converted to glyoxylate by D-amino acid oxidase
Side Effects and Precautions Known Risks (Animal Studies + Anecdotal Reports) Potential for over-stimulation of neurogenesis , which is beneficial short-term but may carry unknown long-term risks Some users report: Mild headaches Irritability or emotional blunting Temporary insomnia if taken late in the day Theoretical Risk: Tumor Growth
R 3 is H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 2 -C 7 heterocycloalkyl, optionally substituted C 6 -C 10 aryl, optionally substituted C 3 -C 9 heteroaryl, OR 6 , NR 5 R 6 , C(O)R 7 , -0O 2 R 6 , C(O)NR 5 R 6 , N(R 5 )C(O)R 7 , N(R 5 )CO 2 R 7 , NHS(O) 2 R 7 , S(O) 2 NR 5 R 6 , or R 2 and R 3 together form an optionally substituted C 2 -C 7 heterocycloalkyl ring
Together, these peptides offer a multi-mechanistic approach to metabolic and body composition research