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They were treated with vehicle, Tamoxifen (30 mg/kg, oral gavage), or a combination of Tamoxifen and Sorafenib (30 mg/kg, oral gavage)

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CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI

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The inflammasome inflammatory cascade may be further intensified by HIF-1 feed-back loops with cytokines like IL-6, which is upregulated in proinflammatory conditions and with HIF-1 stabilization (Xing and Lu, 2016)

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