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Media grade IGF-1 LR3 is more commonly used in commercial cell culture vs mammalian and can also be used as a research reagent at an economical cost to enable studies where biological potency is of less value

While urinary excretion of VC metabolites (oxalate, threonate) maintains systemic balance, prolonged deficiency ( ShacterEet alAscorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

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