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They help you feel full, slow gastric emptying, and support weight loss, in turn improving blood sugar control, pancreatic efficiency, and insulin response, says Chervenak

Serious side effects may include vision changes, an allergic reaction, acute pancreatitis, kidney or gallbladder issues, cardiac issues, and drug abuse

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4 A 2025 mechanistic study using RAMP1/RAMP3 knockout mice demonstrated this dependence directly: cagrilintide activated area postrema neurons and reduced body weight in wild-type animals but had essentially no effect in mice lacking these receptors, pinning its action to the AMY and AMY subtypes in the hindbrain

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