Sleep deprivation impairs molecular clearance from the human brain
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It has been found to aid in the shielding of the digestive tract and reducing inflammation, which is a common symptom of many gastrointestinal disorders
Other reasons include: bariatric surgery or bowel resection, age, those with GI diseases such as Crohns and Celiac, people taking Metformin to control their blood sugar and thos taking proton pump inhibitors (Prevacid, Prilosec, etc) for chronic heartburn