Results show that people taking GLP-1 drugs were 27% more likely to develop GERD and 55% more likely to have GERD complications, when compared to people taking SGLT-2 inhibitors
This article breaks down the good, the bad, and the ugly of GLP-1 weight loss medications, with a special focus on lean muscle loss, metabolic slowdown, weight regain, and the long-term consequences that many people are not told about
Initiation and titration should follow product-specific protocols: Ozempic: Begin with 0.25 mg weekly for 4 weeks, then increase to 0.5 mg weekly, with further titration to 1 mg and potentially 2 mg weekly as tolerated Wegovy: Begin with 0.25 mg weekly for 4 weeks, then increase monthly through 0.5 mg, 1 mg, 1.7 mg, to a maintenance dose of 2.4 mg weekly Rybelsus: Begin with 3 mg once daily for 30 days, then increase to 7 mg daily, with further titration to 14 mg daily as needed [7] [8] MS patients may benefit from slower titration schedules if gastrointestinal tolerability is problematic
GLP-1 agonists have proven revolutionary for diabetes and obesity treatment, with extensive evidence supporting their efficacy and safety
Ligands were added immediately prior to reading on a Mithras LB 940 multimode microplate reader (emission filters at 400 nm and 515 nm)
