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Since GLP-1 RAs can slow down the movement of food through the digestive system, this may result in food remaining in the stomach for longer periods than usual, leading to symptoms characteristic of gastroparesis such as nausea, vomiting, bloating, and abdominal discomfort

More details are available in this guide

This scenario has come about, in part, because of the social media furore and celebrity endorsements of GLP-1 agonists which have created massive hype and demand

Generally, brief excursions up to 25C for a few hours may not significantly impact quality, but repeated or prolonged exposure to elevated temperatures will accelerate degradation