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IDH1 mutations cause significant changes in enzymatic reactions, catalyzing the large-scale conversion of -ketoglutarate (2-KG) to 2-hydroxyglutarate (2-HG), and cause significant changes in the cells metabolic system

It does not employ the prescribing doctors directly

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The World Obesity Federation (WOF) estimates that obesity costs China around US$283.3 billion in GDP loss in 2020 [2]