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Wegovy, containing the active ingredient semaglutide, has emerged as a viable treatment option for weight management post-gastric sleeve surgery

Retatrutide improves insulin sensitivity through GLP-1 and GIP pathways, while growth hormone can transiently increase insulin resistance

This early momentum builds confidence and reinforces behavior changes

Understanding how injections work, where to inject, and what mistakes to avoid helps reduce discomfort, minimise side effects, and ensure the medication works as intended

During the initial period, leukocyte-derived MMP-9 and brain-derived MMP-2 are involved, and later, MMP-3 and MMP-9, angiogenesis, and vasogenic edema may occur, which can destroy NVUs and exacerbate the destruction of the BBB [120, 121]