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Larger needles, rapid injections, or reused needles can be painful

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Both influence mitochondrial function, inflammatory tone, and the molecular machinery that governs neuronal survival and repair, engaging the same PI3K-Akt signaling pathway established earlier, now operating within neurons rather than peripheral tissue

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A study from the National Library of Medicine suggests that whey protein may be especially effective at triggering this response, but most complete protein sources work well