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The mutations G12R, R33Q, and R42P in the UBL domain of parkin significantly reduced the ability of PINK1 to phosphorylate the protein (McLelland et al., 2018)

Data availability The data used to support the findings of this study are included in the article

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Liposomal Vitamin C may offer improved absorption for some individuals, although regular Vitamin C formulations are also commonly used.