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Their hypothesis is that NAC may improve renal function, reduce fluid requirements, and lower tissue edema

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References Mller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, Flatt PR, Fritsche A, Gribble F, Grill HJ, Habener JF, Holst JJ, Langhans W, Meier JJ, Nauck MA, Perez-Tilve D, Pocai A, Reimann F, Sandoval DA, Schwartz TW, Seeley RJ, Stemmer K, Tang-Christensen M, Woods SC, DiMarchi RD, Tschp MH

Signal 4 , ra46 (2011)

GLP-1 agonist mechanism of action in cardiovascular tissues Once activated, GLP-1 receptors trigger multiple signaling pathways that collectively contribute to cardioprotection