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A team at the German Center for Immunotherapy, Erlangen University Hospital, has achieved a world-first by successfully treating a 21-year-old woman with therapy-resistant ulcerative colitis using CD19 CAR-T cell therapy

If you've lost less than 5%, options include: Titrating to a higher Zepbound dose Adding a second medication (e.g., metformin, topiramate) Switching to a different GLP-1 or GLP-1/GIP medication Reassessing diet, exercise, and behavioral factors Most patients who switch from Wegovy to Zepbound and titrate to at least 7.5 mg reach the 5% threshold by week 16

Yu Y, Hao G, Zhang Q, Hua W, Wang M, Zhou W, Zong S, Huang M, Wen X