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The average age at diagnosis varied depending on the clinical setting of malignant peripheral nerve sheath tumors

The activation of adenylyl cyclase leads to increased intracellular cAMP concentrations, which subsequently activate protein kinase A (PKA) and other downstream effectors including EPAC2 and calcium channels

( A ) Mouse caSMCs were transfected with a combination of 4 MTP-specific siRNAs, and relative Mtpa mRNA expression was measured by reverse transcription PCR versus control siRNA

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