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The risk of substance use was also reduced The findings showed that GLP-1 medication use, especially semaglutide, was associated with fewer psychiatric-related hospitalizations and sick leave

77 However, another RCT in patients with obesity did not observe significant improvements in PASI and DLQI scores compared to placebo after 8 weeks of liraglutide (initial dose of 0.6 mg/d, titrated to 1.8 mg/d) treatment

Thats not a reason to ignore it, but it is a reason not to panic

Our study has several limitations: first, this is a retrospective study, so selection bias cannot be avoided

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