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The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation
27(5): 479484 No EOF Notification: 73573/29-7-2021 The EOF notification number does not constitute a marketing authorization license from EOF
The genetic or pharmacological restoration of GPX4 suppresses neutrophil ferroptosis and abrogates downstream autoimmunity, underscoring GPX4 as a checkpoint that constrains iron-driven inflammation (206, 217)
Genetic variation in glutathione synthesis genes (GCLC, GCLM) and detoxification pathways (GST polymorphisms) influences baseline glutathione levels and responsiveness to supplementation
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