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Glutathione is an abundant thiol peptide present in animal cells and plays a critical role in maintaining cellular redox potential 21,22

To create the glutathione model used in this paper, we took the model from [11] and added the glutathione pathway, homocysteine, cystathionine, cysteine, glutamylcysteine, GSH, and GSSG [Figure 1] from a previous model of glutathione metabolism [14]

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Thus, sterile water for injection (or saline without preservative, depending on instructions) would be used for dissolving drugs given by these routes