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In a recent study on active forgetting of cold shock-sensitive or anesthesia-sensitive memory (ASM) and cold shock-insensitive or anesthesia-resistant memory (ARM) in Drosophila , it was found that the Arp2/3 complex was only required for Cdc42/WASP mediated ARM forgetting but not for Rac1/WAVE mediated ASM forgetting, and instead, Rac1/WAVE might function through another protein called Dia ( FIGURE 3 Rho GTPases in Memory Ample studies have indicated that Rho GTPases are involved in learning and memory

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inflamed colonic tissue shows high expression