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Compounded GLP1s filled a gap during shortages, but as supply stabilizes, regulators are signaling that safety and consistency will outweigh affordability

Among the most notable are MSDC-0160 (PNU-91325) and MSDC-0602K, which show potent insulin-sensitizing effects in preclinical 52,53,54 and clinical 53,55 studies despite exhibiting much reduced ability to bind and signal via PPAR 51