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This article will go upstream of that process, looking at how oxidative stress specifically oxidative stress from mitochondrial dysfunction changes the brain in ways that can cause depression

Even small amounts of selenium are sufficient for correct DIO activity, but a reduced selenium intake affects GPx expression and function, leading to impaired antioxidant activity in thyroid cells

and the interplay between the endoplasmic reticulum and actin to drive the contraction of the Drp1 protein to reduce the molecular spacing, leading to the rupture of the OMM and IMM and ultimately triggering mitochondrial fission (Giacomello et al., 2020

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