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Consequently, strategic inhibition of autophagy has been shown to restore antigen presentation and synergize with immunotherapy in preclinical NSCLC models (74)

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thus, clinical application awaits further verification of safety and efficacy, and they are not recommended for routine clinical use at present but are considered as exploratory research directions

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Research from the National Institute on Drug Abuse (NIDA) indicates that over 16 million Americans misuse prescription opioids, many of which contain acetaminophen

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11 , e0006134 (2017)

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