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Moreover, insulin resistance leading to increased insulin levels may contribute to miniaturization of hair follicles, worsening androgenic alopecia Purpose of Study This case report aims to document the effects of tirzepatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, on improving hair density in a patient with androgenic alopecia and insulin resistance

In the SURPASS-2 trial, patients with obesity and T2D who received tirzeapatide (5 mg weekly) achieved greater HbA1c and body weight reductions than those receiving semaglutide (1 mg weekly) during the 40 week study ( With these points in mind, we undertook a broad assessment of published clinical data, curating the body weight loss (% from baseline), glycosylated hemoglobin levels (HbA1c), and nausea responses (% patients reporting) from the SUSTAIN 3, SUSTAIN 7, SCALE Diabetes, SURPASS 2, and STEP 2 trials ( Figures 1AC )

Regardless of the specific contract that gets negotiated, the goal should be to help patients who need access, expand the market for manufacturers and address Medicares concerns about how these drugs will perform long-term

Tirzepatide is different from semaglutide because it works on two receptor pathways instead of one

After reconstitution, use immediately