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Some short-term studies in healthy older adults have been done with GHRH analogs like sermorelin or other secretagogues, and while they sometimes show increases in lean mass or decreases in fat mass, the improvements are modest and can be accompanied by side effects (e.g

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However, calling it the active-B12 test is slightly misleading, because it measures all B12 bound to transcobalaminincluding biologically inactive forms