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When methylation slows, the body struggles to make key molecules such as glutathione and creatine, which mitochondria depend on to stay healthy

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However, the risk of extrahepatic malignancy is unknown in Korean AIH patients

Hasan AA, Kalinina E, Tatarskiy V, Shtil A

NAPQI Formation Highest in FIRST Trimester 43% HIGHER The same Brookhuis 2021 study found: The estimated molar dose fraction of NAPQI was the highest in the first trimester (median (IQR): 11 (9.113.4%), followed by the second (9.0 (7.511%)) and third (8.2 (6.810.1)) trimester compared with non-pregnant women (7.7 (6.49.4%)).[] **This represents a 43% INCREASE in toxic NAPQI formation in the first trimester** (11% vs 7.7%)precisely when the fetal brain is most vulnerable and undergoing critical early development