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Early administration of lactate in rat organotypic hippocampal slices after oxygen-glucose deprivation protected against neuronal death, decreased lesion size and showed better neurologic outcomes in a mouse model of middle cerebral artery occlusion (Berthet et al., 2011), in mouse cortical neuron cultures (Jourdain et al., 2016) and in rat cortex in vivo (Ros et al., 2001)

For analysis, glutathione (GSH), graphene oxide (GO), phenylboronic acid derivative and GO@GSH-FA were dissolved in deuterium oxide (D 2 O)

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However, metabolic changes from weight loss, gastrointestinal effects, and dietary modifications associated with the medication may theoretically contribute to odour changes reported anecdotally by some patients

A 108 , 22162224 (2004)