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An analysis of data from 25,531 participants in the National Health and Nutrition Examination Survey (NHANES) conducted between 2015 and 2020 found that 8,504 individuals, representing approximately 136.8 million adults nationwide, qualified for semaglutide treatment

It belongs to a new generation of incretin-based compounds often called triple agonists because of their ability to simultaneously activate three distinct metabolic receptors: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)

It is the first medication in a class known as dual-agonists

Polymicrogyria: epidemiology, imaging, and clinical aspects in a population-based cohort

Cell 153:12391251 Chhiba KD, Kuang FL (2024) Advancing toward a unified eosinophil signature from transcriptional profiling