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GIP enhances insulin sensitivity while also contributing to appetite regulation

These combined effects result in improved postprandial and fasting glucose levels, along with substantial weight loss that varies by indication and dosetypically 5-13% in type 2 diabetes trials and up to 15-20% in obesity trials at the highest doses (15 mg)

I was using GLP-1 in 2012 for weight loss off label and wrote a book just last year about tirzepatide

You are not deprived of anything

The pivotal Phase 3 REDEFINE 1 trial showed that participants getting the mix lost an average of 25% of their body weight over 68 weeks, compared to 15.8% with semaglutide 2.4mg alone and just 2.4% with placebo