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25,27,28 Consequently, there is growing interest in the development and utilization of novel treatments (be they drugs or medical devices) as add-on or alternative medications to traditional pharmacotherapy

|access-date= requires |url= (help) Greenway FL, Aronne LJ, Raben A

Time of day alterations in function exist, suggesting a potential avenue for targeted therapeutic intervention

Individuals closer to a healthy BMI also tend to lose a higher proportion of fat-free mass (which includes muscle) compared to those with more body fat to lose