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Riecke BF, Christensen R, Christensen P, Leeds AR, Boesen M, Lohmander LS et al

PLoS ONE 8:e62687

Clinical observations describing reduced protein intake, variability in lean mass trajectories, and micronutrient insufficiency during pharmacologically induced weight loss [40, 75, 94, 95] suggest that long-term metabolic stability may become sensitive to substrate availability even in the absence of overt deficiency