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The incidences of major depressive disorder, anxiety, and suicidal ideations or attempts, as well as their hazard ratios, are higher in the GLP-1 RA group, indicating an association with GLP-1 RA treatment over time

The child PM started his treatment with a glucose value of 205 mg% at 60 min which was compatible with established clinical diabetes, but upon physicians and parents request, he was included in the protocol (with a prior clarification that he later receives the treatment)

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Since 2006, glucagon-like peptide-1 receptor (GLP-1R) agonists have caused a dramatic change in the treatment of type 2 diabetes, with clinically relevant and sustained effects on glycaemic control and body weight combined with cardioprotective mechanisms [3, 4]