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Exceeding recommended amounts doesn't necessarily produce better results and may increase side effect risk

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This high metabolic rate leads to increased production of reactive oxygen species (ROS) as byproducts of cellular respiration.Presence of Redox-Active Metals: The brain contains transition metals such as iron and copper, which can catalyze the formation of highly reactive hydroxyl radicals through the Fenton reaction.Limited Regenerative Capacity: Unlike some other tissues, neurons have limited regenerative capacity