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Common reported side effects are typically mild: injection site reactions, temporary nausea, or headaches

expounded on the obesity paradox, suggesting increased BMD is offset by poor bone quality due to advanced glycation end-products (AGEs) accumulation, impaired osteoblast function, and uncoupled bone turnover favoring resorption

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This metabolic delay could counteract semaglutides efforts to improve weight management, making it harder for the medication to do its job