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Participants who maintained continuous treatment kept their weight loss stable, while those who stopped experienced steady upward weight movement

Our form asks for a lot of information that isn't entirely relevant to semaglutide, but that's because we use it for most of our products, rather than managing a dozen different forms based on what you want

Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)